Covers GPU and accelerator programming for research software: choosing a programming model (CUDA, HIP, SYCL, OpenACC, OpenMP offloading), GPU libraries, language bindings such as CuPy, PyCUDA and CUDA.jl, portability layers like Kokkos and Raja, source-to-source translation, kernel profiling and auto-tuning. Use when the user wants to port research code to GPUs, pick between CUDA and portable alternatives, call GPU code from Python or Julia, tune or profile kernels, or mentions HIP, SYCL, OpenACC, Kokkos or Kernel Tuner.