Assess whether a biomedical paper changes clinical practice for the user's specialty (interventional pulmonology, Spain). Distinguishes statistical significance from clinical significance, evaluates population applicability to typical Spanish pulmonary patients, considers availability of interventions in the Spanish healthcare system (SNS) and AEMPS drug approval status, and outputs an actionable judgment. Use after extract-pico and appraise-evidence have run, or independently when the user asks "does this change my practice", "is this clinically relevant", "should I act on this", "is this applicable to my patients", "is this practice-changing", "relevancia clínica".
