Use when drawing or animating with Grease Pencil in Blender 5.x from Python: 2D or 2.5D illustration, frame-by-frame animation, a cutout or part-based 2D character, strokes with pressure, filled shapes with holes, in-betweens and interpolation, onion skin, Line Art outlines, strokes on 3D meshes, NPR or hybrid motion graphics. Also when GP code fails (GPENCIL, frame.strokes, grease_pencil_modifiers), fills do not show, colors render dark, or draw brushes will not run from a script.