Forsy Agent
Skill DeltaNot Forsy-evaluated
Produce a Manhattan plot, QQ plot, and a QC summary (genomic inflation λ_GC, count of genome-wide-significant and suggestive hits, list of independent lead SNPs) from a GWAS summary statistics file. Auto-detects common column-name conventions (`SNP/rsid/variant_id`, `CHR/chromosome/hm_chrom`, `BP/position/base_pair_location`, `P/p_value`). Subsamples low-significance variants to keep plots fast (~seconds) on full HM3-scale or 1KG-scale sumstats. Writes a sidecar `.manhattan_qq.json` manifest citing the input dataset's OKG node when `$OKG_REPO` is set. Use when a user asks for a Manhattan plot, QQ plot, genomic-inflation check, or a quick QC pass on a GWAS sumstats file.